If you choose to use fentanyl, there are some practices that can help you minimize the risk of an overdose. Fentanyl is a synthetic opioid that can be about 50 times as potent as heroin. The dose in a medical setting aims to use the least amount of the drug to achieve the desired effect of pain control.

If you buy drugs illegally, there is a chance fentanyl can be in them. People making illegal fentanyl often do this because it’s less expensive to use fentanyl than other drugs. After you’ve taken an opioid like fentanyl for a long time, your brain gets used to the drug. After a fentanyl treatment, you may have side effects that hinder your thinking and reactions or cause dizziness or drowsiness.
Just a couple dozen pounds of fentanyl were seized along the northern US border with Canada last year, CBP data shows, and experts say that the illicit networks in Canada are almost entirely separate from those in the US. Most of the precursor ingredients “are pretty basic chemicals with wide-scale applications, so hiding the shipments is not very complicated,” said Vanda Felbab-Brown, a senior fellow at the Brookings Institute who has led various initiatives centered on the opioid epidemic and global drug policy. Large shipments of precursor ingredients for illicit fentanyl are sent from China to Mexico, where they are processed in labs and the final product is smuggled over the border into the US. The US imports the vast majority of medical fentanyl from China, which is shipped directly in finished form. Injections may be used during or after surgery, for example, while patches help treat persistent pain in patients that may have become tolerant to other treatments. Police evidence that looked like black tar heroin actually was heroin in 95% of cases, suggesting that fentanyl was rarely in “heroin” in 2020.
Treating Fentanyl Addiction
- Furthermore, a 2017 study suggested the efficacy of fentanyl lozenges in children as young as five, weighing as little as 13 kg.
- Counseling can help you learn new behavioral patterns, stick with medication use, and reroute your thinking pathways.
- But these tips can reduce some of that risk and lower your chances of overdose, infection, or other problem.
- Sometimes people freeze fentanyl patches and cut them into smaller portions.
- The fentanyl supply chain in Mexico consists of a vast and elusive network, potentially involving hundreds of players.
With repeated use, the brain adapts to the drug, making it hard to feel pleasure without it. People who use methamphetamine are also sometimes accidentally exposed to fentanyl. Chinese chemical companies are making more ingredients for illegal fentanyl than ever, including N-Phenyl-4-piperidinamine, which Mexican cartels purchase to make into fentanyl. Fentanyl is often found mixed into heroin, cocaine and methamphetamine, according to the CDC.
How Does Fentanyl Make People Feel?
If your loved one is struggling with opioid use, the resources below may be helpful. To put it in perspective, it’s 50 to 100 times more potent than morphine. Prescription fentanyl is available under such names as Actiq®, Duragesic®, and Sublimaze® in the form of tablets, an injectable liquid, lozenges and patches. It is safe to touch the person and items that may have fentanyl on them (like a doorknob) because fentanyl cannot be absorbed through the skin with casual use (Connolly, 2022). The DEA has found an average of 2.4 milligrams of fentanyl in the pills they test (DEA, 2024). Fentanyl can be illegally mixed into other substances, including heroin, cocaine, ecstasy, and methamphetamine (NIDA, 2021).

The drug can be manufactured illegally. This more recent version of fentanyl comes in bright colors. Test strips to detect fentanyl are inexpensive and typically give results within 5 minutes, which can be the difference between life or death.
For Treatment Providers
Common routes of naloxone administration include IV, IM, IN, or subcutaneous (SC). Naloxone/naltrexone are robust opioid antagonists that function by blocking µ-receptors. The use of fentanyl citrate injection with CYP3A4 inducers or stopping the CYP3A4 inhibitor will require close and repetitive monitoring of the patient. If the patient has used a monoamine oxidase inhibitor in the previous 14 days, fentanyl is contraindicated. This article focuses on injectable fentanyl; more detailed coverage of the transdermal formulation is available in the StatPearls specific article on transdermal fentanyl. The transdermal patch is for the long-term management of pain.